Kongunadu Research Journal
Vol. 6 No. 1 (2019): Vol 6, Iss 1, Year 2019
Articles

IN VITRO CYTOTOXICITY POTENTIAL OF ETHANOL EXTRACT OF SYZYGIUM SAMARANGENSE (Wt.)

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  • Poonkodi k,
  • Mini R,
  • Vimaladevi K,
  • Prabhu V,
  • Anusuya M,
  • Karthigai priya M,
  • Saranya K.S
Poonkodi k
Department of Chemistry, Nallamuthu Gounder Mahalingam College, Pollachi, Coimbatore-642001, Tamil Nadu, India.
Mini R
Department of Chemistry, Nallamuthu Gounder Mahalingam College, Pollachi, Coimbatore-642001, Tamil Nadu, India.
Vimaladevi K
Department of Chemistry, Nallamuthu Gounder Mahalingam College, Pollachi, Coimbatore-642001, Tamil Nadu, India.
Prabhu V
Department of Chemistry, Nallamuthu Gounder Mahalingam College, Pollachi, Coimbatore-642001, Tamil Nadu, India.
Anusuya M
Department of Chemistry, Nallamuthu Gounder Mahalingam College, Pollachi, Coimbatore-642001, Tamil Nadu, India.
Karthigai priya M
Department of Chemistry, Nallamuthu Gounder Mahalingam College, Pollachi, Coimbatore-642001, Tamil Nadu, India.
Saranya K.S
Department of Chemistry, Nallamuthu Gounder Mahalingam College, Pollachi, Coimbatore-642001, Tamil Nadu, India.
DOI: https://doi.org/10.26524/krj283
Published June 30, 2019
Keywords
  • S. samarangense, In vitro cytotoxicity, HeLa cell and MTT assay
How to Cite
k, P., R, M., K, V., V, P., M, A., M, K. priya, & K.S, S. (2019). IN VITRO CYTOTOXICITY POTENTIAL OF ETHANOL EXTRACT OF SYZYGIUM SAMARANGENSE (Wt.). Kongunadu Research Journal, 6(1), 30-32. https://doi.org/10.26524/krj283

Abstract

The present investigation is carried out to study the invitro cytotoxicity of ethanol extract of Syzygium samarangense leaves on HeLa cell line by using MTT assay. Ethanol extract of S. samarangense showed concentration dependent activity on HeLa cell line with IC50 value of 40.5 μg/ml which shows that ethanol extract of S. samarangense posses significant cytoxicity.Moreover the preliminary phytochemical screening showed the presence of fatty acids, alkaloids, flavonoids, terphenoids, saponins, tannins and steroids which are responsible for its cytotoxicity. There are only a few reports are available for cytotoxicity of ethanol extract of S. samarangense.

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