SYNTHESIS, CHARACTERIZATION AND ANTIBACTERIAL STUDIES ON DIVALENT TRANSITION METAL COMPLEXES OF HYDRAZINE WITH ARYL SUBSTITUTED ACETIC ACIDS

Abstract

Metal phenylacetate Sesquihydrazinate hydrates of the formula M(PhAc)2.1.5N2H4.H2O where M=Co,Ni or Cd and Metal phenoxyacetate Sesquihydrazinate hydrates M(PhOAc)2.1.5N2H4.H2O Where M=Co, Ni , Cd or Mn have been prepared and characterized by analytical, IR spectral and thermal studies. The composition of complexes have been determined by analytical studies. Infrared spectral data indicate that the bidentate bridging by hydrazine molecules and monodentate coordination by carboxylate ions to the cental metal ion. Thermogravimetry (TG) and differential thermal analyses (DTA) in air have been used to study the thermal behaviour of the complexes. The simultaneous TG-DTA curves of all the complexes in air resultedin the formation of respective metal or metal oxide as final residue. These complexes decompose exothermically either in single step or decompose through respective metal carboxylate intermediates. The antibacterial activity of the prepared complexes screened against Staphylococcus aureus, Escherichia coli, Pseudomonas aeruginosa and Proteus mirabilis