Kongunadu Research Journal
Vol. 2 No. 1 (2015): Vol 2, Iss 1, Year 2015
Articles

SYNTHESIS, CHARACTERIZATION, DNA BINDING AND ANTIBACTERIAL ACTIVITY OF RUTHENIUM(III) COMPLEX CONTAINING MIXED LIGANDS

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  • Sampath K,
  • Jayabalakrishnan C
Sampath K
Department of Chemistry, Kumaraguru College of Technology, Coimbatore – 641 006, Tamil Nadu, India.
Jayabalakrishnan C
P.G & Research Department of Chemistry, Sri Ramakrishna Mission Vidyalaya College of Arts and Science, Coimbatore-641020
DOI: https://doi.org/10.26524/krj60
Published June 30, 2015
Keywords
  • Ruthenium(III) complexes, Thiosemicarbazones, DNA binding, Cytotoxicity.
How to Cite
K, S., & C, J. (2015). SYNTHESIS, CHARACTERIZATION, DNA BINDING AND ANTIBACTERIAL ACTIVITY OF RUTHENIUM(III) COMPLEX CONTAINING MIXED LIGANDS. Kongunadu Research Journal, 2(1), 24-28. https://doi.org/10.26524/krj60

Abstract

Ruthenium(III) complex, [RuBr2(AsPh3)2L] (where L = (E)-2-(2-chlorobenzylidene)-Nmethylhydrazinecarbothioamide) have been synthesized. Structural features of the complex were determined by various physico-chemical and spectral techniques. DNA binding of the complex was investigated by absorption spectroscopy which indicated that the complex bind to DNA via intercalation and this complex ind strongly than ligand. The complex has shown significant growth inhibition activity against a panel of bacteria which indicating the pharmacological significance of the ruthenium(III) complex.

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