Kongunadu Research Journal
Vol. 2 No. 1 (2015): Vol 2, Iss 1, Year 2015
Articles

SYNTHESIS OF ISOXAZOLO AND PYRAZOLINO ANNELATED CARBAZOLES FROM 2-(3'-(2'-CHLORO) QUINOLIDINE)-1-OXO-1, 2, 3, 4-TETRAHYDROCARBAZOLE AND 2-CHLORO-3-FORMYLQUINOLINE

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  • Sangeetha V
Sangeetha V
Department of Chemistry, Kongunadu Arts and Science College, Coimbatore 641 029, India.
DOI: https://doi.org/10.26524/krj61
Published June 30, 2015
Keywords
  • 1-Oxo-1,2,3,4-tetrahydrocarbazole, 2-chloro-3-formylquinoline, 2-(3'-(2'-chloro)quinolidine)-1- oxo-1,2,3,4-tetrahydrocarbazole, 4,5-dihydro-3-3'-(2'-chloro)quinoline-isoxazolo[3,4-a]carbazole, 3'-(2'- chloro)-quinoline-3,3a,4,5-tetrahydro-2H-pyrazolino[3,4-a]carbazole.
How to Cite
V, S. (2015). SYNTHESIS OF ISOXAZOLO AND PYRAZOLINO ANNELATED CARBAZOLES FROM 2-(3’-(2’-CHLORO) QUINOLIDINE)-1-OXO-1, 2, 3, 4-TETRAHYDROCARBAZOLE AND 2-CHLORO-3-FORMYLQUINOLINE. Kongunadu Research Journal, 2(1), 29-31. https://doi.org/10.26524/krj61

Abstract

1-Oxo-1,2,3,4-tetrahydrocarbazole (1) on mixed aldol condensation with 2-chloro-3-formylquinoline (2) ielded 2-(3'-(2'-chloro)quinolidine)-1-oxo-1,2,3,4-tetrahydrocarbazole (3), which was further treated with hydroxylamine hydrochloride and hydrazine hydrate in separate reactions to afford 4,5-dihydro-3-3'-(2'-
chloro) quinoline -isoxazolo [3,4-a]carbazole (4) and 3'-(2'-chloro)- quinoline- 3,3a,4,5- tetrahydro- 2Hpyrazolino [3,4-a]carbazole (5). The prepared compounds were elaluated for their invitro antibacterial and antifungal activities against certain pathogenic fungal and bacterial strains.

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